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Ray S., Thormann U., Kramer I., Sommer U., Budak M., Schumacher M., Bernhardt A., Lode A., Kern C., Rohnke M., Heiss C., Lips K.S., Gelinsky M., Alt V.. Mesoporous Bioactive Glass-Incorporated Injectable Strontium-Containing Calcium Phosphate Cement Enhanced Osteoconductivity in a Critical-Sized Metaphyseal Defect in Osteoporotic Rats. Bioengineering (Basel). 2023 Oct 16;10(10):1203. doi: 10.3390/bioengineering10101203. PMID: 37892933; PMCID: PMC10604136

Dharmalingam B., Singh P., Schramm P., Birklein F., Kaps M., Lips K.S., Szalay G., Blaes F., Tschernatsch M. Autoantibodies from patients with complex regional pain syndrome (CRPS) induce pro-inflammatory effects and functional disturbances on endothelial cells in vitro. Pain. 2022 Dec 1;163(12):2446-2456. doi: 10.1097/j.pain.0000000000002646. Epub 2022 Apr 4

Burk J., Melzer M., Hagen A., Lips K.S., Trinkaus K., Nimptsch A., Leopold J. (2021) Phospholipid Profiles for Phenotypic Characterization of Adipose-Derived Multipotent Mesenchymal Stromal Cells. FRONT CELL DEV BIOL, 9: 784405

Hemm, F.; Fijak, M.; Belikan, J.; Kampschulte, M.; El Khassawna, T.; Pilatz, A.; Heiss, C.; Lips, K.S. Bone Status in a Mouse Model of Experimental Autoimmune-Orchitis. Int J Mol Sci. 2021 Jul 23;22(15):7858. doi: 10.3390/ijms22157858.

Spreda, M.; Hauptmann, N.; Lehner, V.; Biehl, C.; Liefeith, K.; Lips, K.S. Porous 3D scaffolds enhance MSC vitalitiy and reduce osteoclast activity. Molecules. 2021 Oct 16;26(20):6258. doi: 10.3390/molecules26206258.

Loy, T.L.; Vehlow, D.; Kauschke, V.; Müller, M.; Heiss, C.; Lips, K.S. Effects of BDNF and PEC Nanoparticles on Osteocytes. Molecules. 2020 Sep 10;25(18):E4151. doi: 10.3390/molecules25184151

Fölsch, C.; Dharma, J.; Fonseca Ulloa, C.A.; Lips, K.S.; Rickert, M.; Pruss, A.; Jahnke A. Influence of thermodisinfection on microstructure of human femoral heads: duration of heat exposition and compressive strength. Cell Tissue Bank. 2020 Sep;21(3):457-468. doi: 10.1007/s10561-020-09832-5. Epub 2020 Apr 20.

Alagboso, F.I.; Budak, M.; Sommer, U.; Ray, S.; Kaiser, A.; Kampschulte, M.; Henss, A.; Dürselen, L.; Biehl, C.; Lips, K.S.; Heiss, C.; Thormann, U.; Alt, V. Establishment of a clinically relevant large animal model to assess the healing of metaphyseal bone. Eur Cell Mater. 2019 Jun 20;37:444-466. doi: 10.22203/eCM.v037a27.

Kauschke, V.; Hessland, F.M.; Vehlow, D.; Müller, M.; Heiss, C.; Lips, K.S. High Concentrations of Polyelectrolyte Complex Nanoparticles Decrease Activity of Osteoclasts. Molecules. 2019 Jun 25;24(12). pii: E2346. doi: 10.3390/molecules24122346.

Baumann, L.; Kauschke, V.; Vikman, A.; Dürselen, L.; Krasteva-Christ, G.; Kampschulte, M.; Heiss, C.; Yee, K.T.; Vetter, D.E.; Lips, K.S. Deletion of nicotinic acetylcholine receptor alpha9 in mice resulted in altered bone structure. Bone. 2019 Mar;120:285-296. doi: 10.1016/j.bone.2018.11.003. Epub 2018 Nov 7.

Brunotte, M.; Rupp, M.; Stötzel, S.; Sommer, U.; Mohammed, W.; Thormann, U.; Heiss, C.; Lips, K.S.; Domann, E.; Alt, V. A new small animal model for simulating a two-stage-revision procedure in implant-related methicillin-resistant Staphylococcus aureus bone infection. Injury. 2019 Nov;50(11):1921-1928. doi: 10.1016/j.injury.2019.08.017. Epub 2019 Aug 15

Kauschke, V.; Schneider, M.; Jauch, A.; Schumacher, M.; Kampschulte, M.; Rohnke, M.; Henss, A.; Bamberg, C.; Trinkaus, K.; Gelinsky, M.; Heiss, C.; Lips, K.S. Effects of a Pasty Bone Cement Containing Brain-Derived Neurotrophic Factor-Functionalized Mesoporous Bioactive Glass Particles on Metaphyseal Healing in a New Murine Osteoporotic Fracture Model. Int J Mol Sci. 2018 Nov 9;19(11). pii: E3531. doi: 10.3390/ijms19113531.

Franke, J.; Brobeil, A.; Lips, K.S.; Gattenloehner, S.; Franke, A.P.; Hohendorff, B.; Alt, V.; Schnettler, R. Importance of Mechanoreceptors and Other Neural Structures Within the Anterior Intermeniscal Ligament in the Etiology of Anterior Knee Pain After Tibial Nailing. J Orthop Trauma. 2018 Oct;32(10):526-533. doi: 10.1097/BOT.0000000000001258.

Al Khasawnah, Q.; Hassan, F.; Malhan, D.; Engelhardt, M.; Daghma, D.E.S.; Obidat, D.; Lips, K.S.; El Khassawna, T.; Heiss, C.  Nonsurgical Clinical Management of Periapical Lesions Using Calcium Hydroxide-Iodoform-Silicon-Oil Paste. Biomed Res Int. 2018 Feb 12;2018:8198795. doi: 10.1155/2018/8198795. eCollection 2018.

Henss, A.; Otto, S.K.; Schaepe, K.; Pauksch, L.; Lips, K.S.; Rohnke, M. High resolution imaging and 3D analysis of Ag nanoparticles in cells with ToF-SIMS and delayed extraction. Biointerphases. 2018 Feb 28;13(3):03B410. doi: 10.1116/1.5015957.

Kauschke, V.; Gebert, A.; Calin, M.; Eckert, J.; Scheich, S.; Heiss, C.; Lips, K.S. Effects of new beta-type Ti-40Nb implant materials, brain-derived neurotrophic factor, acetylcholine and nicotine on human mesenchymal stem cells of osteoporotic and non osteoporotic donors. PLoS One. 2018 Feb 28;13(2):e0193468. doi: 10.1371/journal.pone.0193468. eCollection 2018.

Mannala, G.K.; Koettnitz, J.; Mohamed, W.; Sommer, U.; Lips, K.S.; Spröer, C.; Bunk, B.; Overmann, J.; Hain, T.; Heiss, C.; Domann, E.; Alt, V. Whole-genome comparison of high and low virulent Staphylococcus aureus isolates inducing implant-associated bone infections. Int J Med Microbiol. 2018 Apr 25. pii: S1438-4221(17)30603-3. doi: 10.1016/j.ijmm.2018.04.005. [Epub ahead of print]

Nachlinger, R.J.; Kauschke, V.; Trinkaus, K.; El Khassawna, T.; Heiss, C.; Lips, K.S. Application of donepezil increased collagen 1 expression in mesenchymal stroma cells of an ovine osteoporosis model. J J Musculoskelet Neuronal Interact. 2018 Sep 1;18(3):354-365.

Ray, S.; Thormann, U.; Eichelroth, M.; Budak, M.; Biehl, C.; Rupp, M.; Sommer, U.; El Khassawna, T.; Alagboso, F.I.; Kampschulte, M.; Rohnke, M.; Henß, A.; Peppler, K.; Linke, V.; Quadbeck, P.; Voigt, A.; Stenger, F.; Karl, D.; Schnettler, R.; Heiss, C.; Lips, K.S.; Alt, V. Strontium and bisphosphonate coated iron foam scaffolds for osteoporotic fracture defect healing. Biomaterials. 2018 Mar;157:1-16. doi: 10.1016/j.biomaterials.2017.11.049. Epub 2017 Dec 1.

Daghma, D.E.S.; Malhan, D.; Simon, P.; Stötzel, S.; Kern, S.; Hassan, F.; Lips, K.S.; Heiss, C.; El Khassawna, T. Computational segmentation of collagen fibers in bone matrix indicates bone quality in ovariectomized rat spine. J Bone Miner Metab. 2017 Jun 6. doi: 10.1007/s00774-017-0844-5. [Epub ahead of print]

El Khassawna, T.; Daghma, D.E.S.; Stoetzel, S.; Ray, S.; Kern, S.; Malhan, D.; Alt, V.; Thormann, U.; Henß, A.; Rohnke, M.; Stengel, A.; Hassan, F.; Maenz, S.; Jandt, K.D.; Diefenbeck, M.; Schumacher, M.; Gelinsky, M.; Lips, K.S.; Heiss, C. Postembedding Decalcification of Mineralized Tissue Sections Preserves the Integrity of Implanted Biomaterials and Minimizes Number of Experimental Animals. Biomed Res Int. 2017;2017:2023853.

El Khassawna, T.; Merboth, F.; Malhan, D.; Böcker, W.; Daghma, D.E.S.; Stoetzel, S.; Kern, S.; Hassan, F.; Rosenbaum, D.; Langenstein, J.; Bauer, N.; Schlagenhauf, A.; Rösen-Wolff, A.; Schulze, F.; Rupp, M.; Hose, D.; Secklinger, A.; Ignatius, A.; Wilke, H.J.; Lips, K.S.; Heiss, C. Osteocyte Regulation of Receptor Activator of NF-κB Ligand/Osteoprotegerin in a Sheep Model of Osteoporosis. Am J Pathol. 2017 Jun 12. pii: S0002-9440(17)30132-3.

Heiss, C.; Kern, S.; Malhan, D.; Böcker, W.; Engelhardt, M.; Daghma, D.E.S.; Stoetzel, S.; Schmitt, J.; Ivo, M.; Kauschke, V.; Lips, K.S.; Tushtev, K.; Rezwan, K.; El Khassawna, T. A New Clinically Relevant T-Score Standard to Interpret Bone Status in a Sheep Model. Med Sci Monit Basic Res. 2017 Oct 2;23:326-335.

Lykhmus, O.; Voytenko, L.P.; Lips, K.S.; Bergen, I.; Krasteva-Christ, G.; Vetter, D.E.; Kummer, W.; Skok, M. Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice. Front Cell Neurosci. 2017 Sept 12. doi: 10.3389/fncel.2017.00282.

Ray, S.; Khassawna, T.E.; Sommer, U.; Thormann, U.; Wijekoon, N.D.; Lips, K.S.; Heiss, C.; Alt, V. Differences in expression of Wnt antagonist Dkk1 in healthy versus pathological bone samples. J Microsc. 2017 Jan;265(1):111-120.

Alt, V.; Cheung, W.H.; Chow, S.K.; Thormann, U.; Cheung, E.N.; Lips, K.S.; Schnettler, R.; Leung, K.S. Bone formation and degradation behavior of nanocrystalline hydroxyapatite with or without collagen-type 1 in osteoporotic bone defects - an experimental study in osteoporotic goats. Injury. 2016 Jun;47 Suppl 2:S58-65.

Augat, P.; Robioneck, P.B.; Abdulazim, A.; Wipf, F.; Lips, K.S.; Alt, V.; Schnettler, R.; Heiss, C. Fixation performance of an ultrasonically fused, bioresorbable osteosynthesis implant: A biomechanical and biocompatibility study. J Biomed Mater Res B Appl Biomater. 2016; 104(1):170-9.

Beckmann, J.; Dittmann, N.; Schütz, I.; Klein, J.; Lips, K.S. Effect of M3 muscarinic acetylcholine receptor deficiency on collagen antibody-induced arthritis. Arthritis Res Ther. 2016 Jan 19;18:17.

Charyeva, O.; Dakischew, O.; Sommer, U.; Heiss, C.; Schnettler, R.; Lips, K.S. Biocompatibility of magnesium implants in primary human reaming debris-derived cells stem cells in vitro. J Orthop Traumatol. 2016; 17(1):63-73.

Kampschulte, M.; Krombach, G.A.; Richards, D.C.; Sender, J.; Lips, K.S.; Thormann, U.; El Khassawna, T.; Ray, S.; Alt, V.; Langheinrich, A.C. Neovascularization of osteoporotic metaphyseal bone defects: A morphometric micro-CT study.  Microvasc Res. 2016 May;105:7-14.

Mohamed, W.; Domann, E.; Chakraborty, T.; Mannala, G.; Lips, K.S.; Heiss, C.; Schnettler, R.; Alt, V. TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress. BMC Microbiology. 2016, 16(1):230.

Ray, S.; Thormann, U.; Sommer, U.; Khassawna, T.E.; Hundgeburth, M.; Henß, A.; Rohnke, M.; Lips, K.S.; Heiss, C.; Heinemann, S.; Hanke, T.; Dürselen, L.; Schnettler, R.; Alt, V. Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats. Injury. 2016 Jan;47 Suppl 1:S52-61.

Vehlow, D.; Schmidt, R.; Gebert, A.; Siebert, M.; Lips, K.S.; Müller, M. Polyelectrolyte Complex Based Interfacial Drug Delivery System with Controlled Loading and Improved Release Performance for Bone Therapeutics. Nanomaterials. 2016; 6(3), 53.

Ternes, S.; Trinkaus, K.; Bergen, I.; Knaack, S.; Gelinsky, M.; Kilian, O.; Heiss, C.; Lips, K.S. Impact of acetylcholine and nicotine on human osteoclastogenesis in vitro. Int Immunopharmacol. 2015 Nov;29(1):215-21.

Nassenstein, C.; Wiegand, S.; Lips, K.S.; Li, G.; Klein, J.; Kummer, W. Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters. Int Immunopharmacol. 2015 Nov;29(1):173-80.

Kauschke, V.; Kneffel, M.; Floel, W.; Hartmann, S.; Kampschulte, M.; Durselen, L.; Ignatius, A.; Schnettler, R.; Heiss, C.; Lips, K.S. Bone status of acetylcholinesterase-knockout mice. Int Immunopharmacol. 2015 Nov;29(1):222-30.

Charyeva, O.; Thormann, U.; Lips, K.S.; Heimann, L.; Sommer, U.; Szalay, G.; Alt, V.; Hort, N.; Schnettler, R.; Rauschmann, M.; Schmidt, S. Histological Comparison of New Biodegradable Magnesium-Based Implants for Maxillofacial Applications. Journal of maxillofacial and oral surgery. 2015a Sep;14(3):637-645.

Charyeva, O.; Feyerabend, F,; Willumeit, R.; Zukowski, D.; Gasqueres, C.; Szakacs, G.; Ahmad Agha, N.; Hort, N.; Gensch, F.; Cecchinato, F.; Jimbo, R.; Wennerberg, A.; Lips, K.S. In vitro resorption of magensium materials and ist effect on surface and surrounding environment. MOJ Toxicol. 2015;1(1):00004. DOI: 10.15406/mojt.2015.02.00004.

Zablotni, A.; Dakischew, O.; Trinkaus, K.; Hartmann, S.; Szalay, G.; Heiss, C.; Lips, K.S. Regulation of acetylcholine receptors during differentiation of bone mesenchymal stem cells harvested from human reaming debris. Int Immunopharmacol. 2015 Nov;29(1):119-26.

El Khassawna, T.; Bocker, W.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Kampschulte, M.; Thormann, U.; Henss, A.; Rohnke, M.; Bauer, N.; Muller, R.; Deutsch, A.; Ignatius, A.; Durselen, L.; Langheinrich, A.; Lips, K.S.; Schnettler, R.; Heiss, C. Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats. Histochem Cell Biol. 2015 Nov;144(5):491-507.

Beckmann, J.; Schubert, J.; Morhenn, H.G.; Grau, V.; Schnettler, R.; Lips, K.S. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res. 2015 Feb;359(2):465-77.

Haupt, M.; Kauschke, V.; Sender, J.; Kampschulte, M.; Kovtun, A.; Durselen, L.; Heiss, C.; Lips, K.S. Bone status of adult female butyrylcholinesterase gene-deficient mice. Int Immunopharmacol. 2015 Nov;29(1):208-14.

Lips, K.S.; Kneffel, M.; Willscheid, F.; Mathies, F.M.; Kampschulte, M.; Hartmann, S.; Panzer, I.; Durselen, L.; Heiss, C.; Kauschke, V. Altered ultrastructure, density and cathepsin K expression in bone of female muscarinic acetylcholine receptor M3 knockout mice. Int Immunopharmacol. 2015 Nov;29(1):201-7.

Lautenschläger, S.; Striegler, C.; Dakischew, O.; Schütz, I.; Szalay, G.; Schnettler, R.; Heiß, C.; Appelhans, D.; Lips, K.S. Effects of dendritic core-shell glycoarchitectures on primary mesenchymal stem cells and osteoblasts obtained from different human donors. J Nanobiotechnology. 2015 Oct 8;13(1):65.

Thormann, U.; Alt, V.; Heimann, L.; Gasquere, C.; Heiss, C.; Szalay, G.; Franke, J.; Schnettler, R.; Lips, K.S. The biocompatibility of degradable magnesium interference screws: an experimental study with sheep. BioMed research international. 2015;2015:943603.

Pauksch, L.; Franke, J.; Schnettler, R.; Lips, K.S. Synergistic toxicity of gentamicin- and nanosilver-doped polymethylmethacrylate bone cement on primary human osteoclasts. Cells, tissues, organs. 2014a;199(5-6):384-392.

Lips, K.S.; Yanko, O.; Kneffel, M.; Panzer, I.; Kauschke, V.; Madzharova, M.; Henss, A.; Schmitz, P.; Rohnke, M.; Bauerle, T.; Liu, Y.; Kampschulte, M.; Langheinrich, A.C.; Durselen, L.; Ignatius, A.; Heiss, C.; Schnettler, R.; Kilian, O. Small changes in bone structure of female alpha7 nicotinic acetylcholine receptor knockout mice. BMC musculoskeletal disorders. 2015b;16:5.

Lorenzetti, M.; Dakischew, O.; Trinkaus, K.; Lips, K.S.; Schnettler, R.; Kobe, S.; Novak, S. Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO(2) coatings. Journal of biomaterials applications. 2015 Jul;30(1):71-84.

Pauksch, L.; Hartmann, S.; Szalay, G.; Alt, V.; Lips, K.S. In vitro assessment of nanosilver-functionalized PMMA bone cement on primary human mesenchymal stem cells and osteoblasts. PloS one. 2014b;9(12):e114740.

Beckmann, J.; Schubert, J.; Morhenn, H.G.; Grau, V.; Schnettler, R.; Lips, K.S. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell and tissue research. 2015 Feb;359(2):465-477.

Mohamed, W.; Sommer, U.; Sethi, S.; Domann, E.; Thormann, U.; Schutz, I.; Lips, K.S.; Chakraborty, T.; Schnettler, R.; Alt, V. Intracellular proliferation of S. aureus in osteoblasts and effects of rifampicin and gentamicin on S. aureus intracellular proliferation and survival. European cells & materials. 2014;28:258-268.

Kilian, O.; Hartmann, S.; Dongowski, N.; Karnati, S.; Baumgart-Vogt, E.; Hartel, F.V.; Noll, T.; Schnettler, R.; Lips, K.S. BDNF and its TrkB receptor in human fracture healing. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2014 Sep;196(5):286-295.

Alt, V.; Kirchhof, K.; Seim, F.; Hrubesch, I.; Lips, K.S.; Mannel, H.; Domann, E.; Schnettler, R. Rifampicin-fosfomycin coating for cementless endoprostheses: antimicrobial effects against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Acta biomaterialia. 2014 Oct;10(10):4518-4524.

Lips, K.S.; Kauschke, V.; Hartmann, S.; Thormann, U.; Ray, S.; Schumacher, M.; Gelinsky, M.; Heinemann, S.; Hanke, T.; Kautz, A.R.; Schnabelrauch, M.; Szalay, G.; Heiss, C.; Schnettler, R.; Alt, V.; Kilian, O. Cholinergic nerve fibers in bone defects of a rat osteoporosis model and their regulation by implantation of bone substitution materials. Journal of musculoskeletal & neuronal interactions. 2014 Jun;14(2):173-188.

Kauschke, V.; Lips, K.S.; Heiss, C.; Schnettler, R. Expression of muscarinic acetylcholine receptors M3 and M5 in osteoporosis. Medical science monitor : international medical journal of experimental and clinical research. 2014;20:869-874.

Khalil, F.; Franzmann, E.; Ramcke, J.; Dakischew, O.; Lips, K.S.; Reinhardt, A.; Heisig, P.; Maison, W. Biomimetic PEG-catecholates for stabile antifouling coatings on metal surfaces: applications on TiO2 and stainless steel. Colloids and surfaces B, Biointerfaces. 2014 May 1;117:185-192.

Fehrendt, H.; Linn, T.; Hartmann, S.; Szalay, G.; Heiss, C.; Schnettler, R.; Lips, K.S. Negative influence of a long-term high-fat diet on murine bone architecture. International journal of endocrinology. 2014;2014:318924.

Thormann, U.; El Khawassna, T.; Ray, S.; Duerselen, L.; Kampschulte, M.; Lips, K.; von Dewitz, H.; Heinemann, S.; Heiss, C.; Szalay, G.; Langheinrich, A.C.; Ignatius, A.; Schnettler, R.; Alt, V. Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats. Injury. 2014 Mar;45(3):487-493.

Govindarajan, P.; Bocker, W.; El Khassawna, T.; Kampschulte, M.; Schlewitz, G.; Huerter, B.; Sommer, U.; Durselen, L.; Ignatius, A.; Bauer, N.; Szalay, G.; Wenisch, S.; Lips, K.S.; Schnettler, R.; Langheinrich, A.; Heiss, C. Bone matrix, cellularity, and structural changes in a rat model with high-turnover osteoporosis induced by combined ovariectomy and a multiple-deficient diet. The American journal of pathology. 2014 Mar;184(3):765-777.

Pauksch, L.; Hartmann, S.; Rohnke, M.; Szalay, G.; Alt, V.; Schnettler, R.; Lips, K.S. Biocompatibility of silver nanoparticles and silver ions in primary human mesenchymal stem cells and osteoblasts. Acta biomaterialia. 2014c Jan;10(1):439-449.

El Khassawna, T.; Bocker, W.; Govindarajan, P.; Schliefke, N.; Hurter, B.; Kampschulte, M.; Schlewitz, G.; Alt, V.; Lips, K.S.; Faulenbach, M.; Mollmann, H.; Zahner, D.; Durselen, L.; Ignatius, A.; Bauer, N.; Wenisch, S.; Langheinrich, A.C.; Schnettler, R.; Heiss, C. Effects of multi-deficiencies-diet on bone parameters of peripheral bone in ovariectomized mature rat. PloS one. 2013;8(8):e71665.

Govindarajan, P.; Schlewitz, G.; Schliefke, N.; Weisweiler, D.; Alt, V.; Thormann, U.; Lips, K.S.; Wenisch, S.; Langheinrich, A.C.; Zahner, D.; Hemdan, N.Y.; Bocker, W.; Schnettler, R.; Heiss, C. Implications of combined ovariectomy/multi-deficiency diet on rat bone with age-related variation in bone parameters and bone loss at multiple skeletal sites by DEXA. Medical science monitor basic research. 2013;19:76-86.

Gruner, D.; Lips, K.S.; Heiss, C.; Schnettler, R.; Kollmann, T.; Simon, P.; Kniep, R. Irregular shaped, assumably semi-crystalline calciumphosphate platelet deposition at the mineralization front of rabbit femur osteotomy: a HR-TEM study. Scanning. 2013 May-Jun;35(3):169-182.

Lips, K.S.; Kauschke, V.; Hartmann, S.; Thormann, U.; Ray, S.; Kampschulte, M.; Langheinrich, A.; Schumacher, M.; Gelinsky, M.; Heinemann, S.; Hanke, T.; Kautz, A.R.; Schnabelrauch, M.; Schnettler, R.; Heiss, C.; Alt, V.; Kilian, O. Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures. PloS one. 2013;8(10):e77259.

Nandigama, R.; Ibanez-Tallon, I.; Lips, K.S.; Schwantes, U.; Kummer, W.; Bschleipfer, T. Expression of nicotinic acetylcholine receptor subunit mRNA in mouse bladder afferent neurons. Neuroscience. 2013 Jan 15;229:27-35.

Alt, V.; Thormann, U.; Ray, S.; Zahner, D.; Durselen, L.; Lips, K.; El Khassawna, T.; Heiss, C.; Riedrich, A.; Schlewitz, G.; Ignatius, A.; Kampschulte, M.; von Dewitz, H.; Heinemann, S.; Schnettler, R.; Langheinrich, A. A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures. Acta biomaterialia. 2013 Jun;9(6):7035-7042.

Schleicher, I.; Lips, K.S.; Sommer, U.; Schappat, I.; Martin, A.P.; Szalay, G.; Hartmann, S.; Schnettler, R. Biphasic scaffolds for repair of deep osteochondral defects in a sheep model. The Journal of surgical research. 2013a Jul;183(1):184-192.

Schleicher, I.; Lips, K.S.; Sommer, U.; Schappat, I.; Martin, A.P.; Szalay, G.; Schnettler, R. Allogenous bone with collagen for repair of deep osteochondral defects. The Journal of surgical research. 2013b Dec;185(2):667-675.

Schlewitz, G.; Govindarajan, P.; Schliefke, N.; Alt, V.; Bocker, W.; Elkhassawna, T.; Thormann, U.; Lips, K.S.; Hemdan, N.Y.; Zahner, D.; Schnettler, R.; Heiss, C. [Ovariectomy and calcium/vitamin D2/D3 deficient diet as a model of osteoporosis in the spine of Sprague-Dawley rats]. Zeitschrift fur Orthopadie und Unfallchirurgie. 2013 Feb;151(1):14-19.

Thormann, U.; Ray, S.; Sommer, U.; Elkhassawna, T.; Rehling, T.; Hundgeburth, M.; Henss, A.; Rohnke, M.; Janek, J.; Lips, K.S.; Heiss, C.; Schlewitz, G.; Szalay, G.; Schumacher, M.; Gelinsky, M.; Schnettler, R.; Alt, V. Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats. Biomaterials. 2013 Nov;34(34):8589-8598.

Bschleipfer, T.; Weidner, W.; Kummer, W.; Lips, K.S. Does bladder outlet obstruction alter the non-neuronal cholinergic system of the human urothelium? Life sciences. 2012 Nov 27;91(21-22):1082-1086.

Heiss, C.; Govindarajan, P.; Schlewitz, G.; Hemdan, N.Y.; Schliefke, N.; Alt, V.; Thormann, U.; Lips, K.S.; Wenisch, S.; Langheinrich, A.C.; Zahner, D.; Schnettler, R. Induction of osteoporosis with its influence on osteoporotic determinants and their interrelationships in rats by DEXA. Medical science monitor : international medical journal of experimental and clinical research. 2012 Jun;18(6):BR199-207.

Hollenhorst, M.I.; Lips, K.S.; Kummer, W.; Fronius, M. Nicotine-induced activation of soluble adenylyl cyclase participates in ion transport regulation in mouse tracheal epithelium. Life sciences. 2012a Nov 27;91(21-22):1009-1012.

Kliemann, K.; Kneffel, M.; Bergen, I.; Kampschulte, M.; Langheinrich, A.C.; Durselen, L.; Ignatius, A.; Kilian, O.; Schnettler, R.; Lips, K.S. Quantitative analyses of bone composition in acetylcholine receptor M3R and alpha7 knockout mice. Life sciences. 2012 Nov 27;91(21-22):997-1002.

Schubert, J.; Beckmann, J.; Hartmann, S.; Morhenn, H.G.; Szalay, G.; Heiss, C.; Schnettler, R.; Lips, K.S. Expression of the non-neuronal cholinergic system in human knee synovial tissue from patients with rheumatoid arthritis and osteoarthritis. Life sciences. 2012 Nov 27;91(21-22):1048-1052.

Wolff, M.; Noreikat, K.; Ibanez-Tallon, I.; Lips, K.S.; Kolle, S.; Kummer, W. Cholinergic receptors in the murine oviduct: inventory and coupling to intracellular calcium concentration. Life sciences. 2012 Nov 27;91(21-22):1003-1008.

Hollenhorst, M.I.; Lips, K.S.; Weitz, A.; Krasteva, G.; Kummer, W.; Fronius, M. Evidence for functional atypical nicotinic receptors that activate K+-dependent Cl- secretion in mouse tracheal epithelium. American journal of respiratory cell and molecular biology. 2012b Jan;46(1):106-114.

Hollenhorst, M.I.; Lips, K.S.; Wolff, M.; Wess, J.; Gerbig, S.; Takats, Z.; Kummer, W.; Fronius, M. Luminal cholinergic signalling in airway lining fluid: a novel mechanism for activating chloride secretion via Ca(2)(+)-dependent Cl(-) and K(+) channels. British journal of pharmacology. 2012c Jun;166(4):1388-1402.

Paddenberg, R.; Tiefenbach, M.; Faulhammer, P.; Goldenberg, A.; Gries, B.; Pfeil, U.; Lips, K.S.; Piruat, J.I.; Lopez-Barneo, J.; Schermuly, R.T.; Weissmann, N.; Kummer, W. Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries. Cardiovascular research. 2012 Mar 15;93(4):702-710.

Alt, V.; Kogelmaier, D.V.; Lips, K.S.; Witt, V.; Pacholke, S.; Heiss, C.; Kampschulte, M.; Heinemann, S.; Hanke, T.; Thormann, U.; Schnettler, R.; Langheinrich, A.C. Assessment of angiogenesis in osseointegration of a silica-collagen biomaterial using 3D-nano-CT. Acta biomaterialia. 2011a Oct;7(10):3773-3779.

Alt, V.; Lips, K.S.; Henkenbehrens, C.; Muhrer, D.; Oliveira Cavalcanti, M.C.; Sommer, U.; Thormann, U.; Szalay, G.; Heiss, C.; Pavlidis, T.; Domann, E.; Schnettler, R. A new animal model for implant-related infected non-unions after intramedullary fixation of the tibia in rats with fluorescent in situ hybridization of bacteria in bone infection. Bone. 2011b May 1;48(5):1146-1153.

Kraus, R.; Peters, F.; Geck, A.; Lips, K.S.; Obert, M.; Roder, C.; Schnabelrauch, M.; Schnettler, R.; Heiss, C. [Adhesive strength of a beta-tricalcium phosphate-enriched bone adhesive]. Zeitschrift fur Orthopadie und Unfallchirurgie. 2011 Jun;149(3):271-278.

Offer, L.; Veigel, B.; Pavlidis, T.; Heiss, C.; Gelinsky, M.; Reinstorf, A.; Wenisch, S.; Lips, K.S.; Schnettler, R. Phosphoserine-modified calcium phosphate cements: bioresorption and substitution. Journal of tissue engineering and regenerative medicine. 2011 Jan;5(1):11-19.

Schirmer, S.U.; Eckhardt, I.; Lau, H.; Klein, J.; DeGraaf, Y.C.; Lips, K.S.; Pineau, C.; Gibbins, I.L.; Kummer, W.; Meinhardt, A.; Haberberger, R.V. The cholinergic system in rat testis is of non-neuronal origin. Reproduction (Cambridge, England). 2011 Jul;142(1):157-166.

Heiss, C.; Schettler, N.; Wenisch, S.; Cords, S.; Schilke, F.; Lips, K.S.; Alt, V.; Schnettler, R. Bond strength of an alkylene bis(dilactoyl)-methacrylate bone adhesive: a biomechanical evaluation in sheep. Journal of biomaterials science Polymer edition. 2010;21(10):1345-1358.

Mikulski, Z.; Hartmann, P.; Jositsch, G.; Zaslona, Z.; Lips, K.S.; Pfeil, U.; Kurzen, H.; Lohmeyer, J.; Clauss, W.G.; Grau, V.; Fronius, M.; Kummer, W. Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration. Respiratory research. 2010;11:133.

En-Nosse, M.; Hartmann, S.; Trinkaus, K.; Alt, V.; Stigler, B.; Heiss, C.; Kilian, O.; Schnettler, R.; Lips, K.S. Expression of non-neuronal cholinergic system in osteoblast-like cells and its involvement in osteogenesis. Cell and tissue research. 2009 Nov;338(2):203-215.

Hecker, A.; Mikulski, Z.; Lips, K.S.; Pfeil, U.; Zakrzewicz, A.; Wilker, S.; Hartmann, P.; Padberg, W.; Wessler, I.; Kummer, W.; Grau, V. Pivotal Advance: Up-regulation of acetylcholine synthesis and paracrine cholinergic signaling in intravascular transplant leukocytes during rejection of rat renal allografts. Journal of leukocyte biology. 2009 Jul;86(1):13-22.

Klein, M.K.; Haberberger, R.V.; Hartmann, P.; Faulhammer, P.; Lips, K.S.; Krain, B.; Wess, J.; Kummer, W.; Konig, P. Muscarinic receptor subtypes in cilia-driven transport and airway epithelial development. The European respiratory journal. 2009 May;33(5):1113-1121.

Shelukhina, I.V.; Kryukova, E.V.; Lips, K.S.; Tsetlin, V.I.; Kummer, W. Presence of alpha7 nicotinic acetylcholine receptors on dorsal root ganglion neurons proved using knockout mice and selective alpha-neurotoxins in histochemistry. Journal of neurochemistry. 2009 May;109(4):1087-1095.

Biallas, S.; Wilker, S.; Lips, K.S.; Kummer, W.; Grando, S.A.; Padberg, W.; Grau, V. Immunohistochemical detection of nicotinic acetylcholine receptor subunits alpha9 and alpha10 in rat lung isografts and allografts. Life sciences. 2007 May 30;80(24-25):2286-2289.

Bschleipfer, T.; Schukowski, K.; Weidner, W.; Grando, S.A.; Schwantes, U.; Kummer, W.; Lips, K.S. Expression and distribution of cholinergic receptors in the human urothelium. Life sciences. 2007 May 30;80(24-25):2303-2307.

Grau, V.; Wilker, S.; Lips, K.S.; Hartmann, P.; Rose, F.; Padberg, W.; Fehrenbach, H.; Wessler, I.; Kummer, W. Administration of keratinocyte growth factor down-regulates the pulmonary capacity of acetylcholine production. The international journal of biochemistry & cell biology. 2007a;39(10):1955-1963.

Zarghooni, S.; Wunsch, J.; Bodenbenner, M.; Bruggmann, D.; Grando, S.A.; Schwantes, U.; Wess, J.; Kummer, W.; Lips, K.S. Expression of muscarinic and nicotinic acetylcholine receptors in the mouse urothelium. Life sciences. 2007 May 30;80(24-25):2308-2313.

Grau, V.; Wilker, S.; Hartmann, P.; Lips, K.S.; Grando, S.A.; Padberg, W.; Fehrenbach, H.; Kummer, W. Administration of keratinocyte growth factor (KGF) modulates the pulmonary expression of nicotinic acetylcholine receptor subunits alpha7, alpha9 and alpha10. Life sciences. 2007b May 30;80(24-25):2290-2293.

Krasteva, G.; Pfeil, U.; Filip, A.M.; Lips, K.S.; Kummer, W.; Konig, P. Caveolin-3 and eNOS colocalize and interact in ciliated airway epithelial cells in the rat. The international journal of biochemistry & cell biology. 2007;39(3):615-625.

Lips, K.S.; Luhrmann, A.; Tschernig, T.; Stoeger, T.; Alessandrini, F.; Grau, V.; Haberberger, R.V.; Koepsell, H.; Pabst, R.; Kummer, W. Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. Life sciences. 2007a May 30;80(24-25):2263-2269.

Lips, K.S.; Wunsch, J.; Zarghooni, S.; Bschleipfer, T.; Schukowski, K.; Weidner, W.; Wessler, I.; Schwantes, U.; Koepsell, H.; Kummer, W. Acetylcholine and molecular components of its synthesis and release machinery in the urothelium. European urology. 2007b Apr;51(4):1042-1053.

Galvis, G.; Lips, K.S.; Kummer, W. Expression of nicotinic acetylcholine receptors on murine alveolar macrophages. Journal of molecular neuroscience : MN. 2006;30(1-2):107-108.

Hecker, A.; Lips, K.S.; Pfeil, U.; Kummer, W.; Padberg, W.; Grau, V. Peripheral choline acetyltransferase is expressed by monocytes and upregulated during renal allograft rejection in rats. Journal of molecular neuroscience : MN. 2006;30(1-2):23-24.

Kummer, W.; Wiegand, S.; Akinci, S.; Schinkel, A.H.; Wess, J.; Koepsell, H.; Haberberger, R.V.; Lips, K.S. Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse. Journal of molecular neuroscience : MN. 2006a;30(1-2):67-68.

Kummer, W.; Wiegand, S.; Akinci, S.; Wessler, I.; Schinkel, A.H.; Wess, J.; Koepsell, H.; Haberberger, R.V.; Lips, K.S. Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse. Respiratory research. 2006b;7:65.

Lips, K.S.; Konig, P.; Schatzle, K.; Pfeil, U.; Krasteva, G.; Spies, M.; Haberberger, R.V.; Grando, S.A.; Kummer, W. Coexpression and spatial association of nicotinic acetylcholine receptor subunits alpha7 and alpha10 in rat sympathetic neurons. Journal of molecular neuroscience : MN. 2006;30(1-2):15-16.

Spies, M.; Lips, K.S.; Kurzen, H.; Kummer, W.; Haberberger, R.V. Nicotinic acetylcholine receptors containing subunits alpha3 and alpha5 in rat nociceptive dorsal root ganglion neurons. Journal of molecular neuroscience : MN. 2006;30(1-2):55-56.

Berse, B.; Szczecinska, W.; Lopez-Coviella, I.; Madziar, B.; Zemelko, V.; Kaminski, R.; Kozar, K.; Lips, K.S.; Pfeil, U.; Blusztajn, J.K. Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro. Brain research Developmental brain research. 2005 Jun 30;157(2):132-140.

Dvorakova, M.; Lips, K.S.; Bruggmann, D.; Slavikova, J.; Kuncova, J.; Kummer, W. Developmental changes in the expression of nicotinic acetylcholine receptor alpha-subunits in the rat heart. Cell and tissue research. 2005 Feb;319(2):201-209.

Lips, K.S.; Bruggmann, D.; Pfeil, U.; Vollerthun, R.; Grando, S.A.; Kummer, W. Nicotinic acetylcholine receptors in rat and human placenta. Placenta. 2005a Nov;26(10):735-746.

Lips, K.S.; Volk, C.; Schmitt, B.M.; Pfeil, U.; Arndt, P.; Miska, D.; Ermert, L.; Kummer, W.; Koepsell, H. Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. American journal of respiratory cell and molecular biology. 2005b Jul;33(1):79-88.

Muller, J.; Lips, K.S.; Metzner, L.; Neubert, R.H.; Koepsell, H.; Brandsch, M. Drug specificity and intestinal membrane localization of human organic cation transporters (OCT). Biochemical pharmacology. 2005 Dec 5;70(12):1851-1860.

Obreja, O.; Biasio, W.; Andratsch, M.; Lips, K.S.; Rathee, P.K.; Ludwig, A.; Rose-John, S.; Kress, M. Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. Brain : a journal of neurology. 2005 Jul;128(Pt 7):1634-1641.

Haberberger, R.V.; Bernardini, N.; Kress, M.; Hartmann, P.; Lips, K.S.; Kummer, W. Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat. Autonomic neuroscience : basic & clinical. 2004 Jun 30;113(1-2):32-42.

Papadopolou, S.; Hartmann, P.; Lips, K.S.; Kummer, W.; Haberberger, R.V. Nicotinic receptor mediated stimulation of NO-generation in neurons of rat thoracic dorsal root ganglia. Neuroscience letters. 2004 May 6;361(1-3):32-35.

Pfeil, U.; Vollerthun, R.; Kummer, W.; Lips, K.S. Expression of the cholinergic gene locus in the rat placenta. Histochemistry and cell biology. 2004 Aug;122(2):121-130.

Lips, K.S.; Pfeil, U.; Reiners, K.; Rimasch, C.; Kuchelmeister, K.; Braun-Dullaeus, R.C.; Haberberger, R.V.; Schmidt, R.; Kummer, W. Expression of the high-affinity choline transporter CHT1 in rat and human arteries. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2003 Dec;51(12):1645-1654.

Bruggmann, D.; Lips, K.S.; Pfeil, U.; Haberberger, R.V.; Kummer, W. Rat arteries contain multiple nicotinic acetylcholine receptor alpha-subunits. Life sciences. 2003 Mar 28;72(18-19):2095-2099.

Distler, C.; Rathee, P.K.; Lips, K.S.; Obreja, O.; Neuhuber, W.; Kress, M. Fast Ca2+-induced potentiation of heat-activated ionic currents requires cAMP/PKA signaling and functional AKAP anchoring. Journal of neurophysiology. 2003 May;89(5):2499-2505.

Haberberger, R.V.; Henrich, M.; Lips, K.S.; Kummer, W. Nicotinic receptor alpha 7-subunits are coupled to the stimulation of nitric oxide synthase in rat dorsal root ganglion neurons. Histochemistry and cell biology. 2003 Sep;120(3):173-181.

Pfeil, U.; Haberberger, R.V.; Lips, K.S.; Eberling, L.; Grau, V.; Kummer, W. Expression of the high-affinity choline transporter CHT1 in epithelia. Life sciences. 2003a Mar 28;72(18-19):2087-2090.

Pfeil, U.; Lips, K.S.; Eberling, L.; Grau, V.; Haberberger, R.V.; Kummer, W. Expression of the high-affinity choline transporter, CHT1, in the rat trachea. American journal of respiratory cell and molecular biology. 2003b Apr;28(4):473-477.

Arredondo, J.; Nguyen, V.T.; Chernyavsky, A.I.; Bercovich, D.; Orr-Urtreger, A.; Kummer, W.; Lips, K.; Vetter, D.E.; Grando, S.A. Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium. The Journal of cell biology. 2002 Oct 28;159(2):325-336.

Bruggmann, D.; Lips, K.S.; Pfeil, U.; Haberberger, R.V.; Kummer, W. Multiple nicotinic acetylcholine receptor alpha-subunits are expressed in the arterial system of the rat. Histochemistry and cell biology. 2002 Dec;118(6):441-447.

Haberberger, R.V.; Pfeil, U.; Lips, K.S.; Kummer, W. Expression of the high-affinity choline transporter, CHT1, in the neuronal and non-neuronal cholinergic system of human and rat skin. The Journal of investigative dermatology. 2002 Oct;119(4):943-948.

Lips, K.S.; Pfeil, U.; Haberberger, R.V.; Kummer, W. Localisation of the high-affinity choline transporter-1 in the rat skeletal motor unit. Cell and tissue research. 2002a Mar;307(3):275-280.

Lips, K.S.; Pfeil, U.; Kummer, W. Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons. Neuroscience. 2002b;115(1):1-5.

Obreja, O.; Rathee, P.K.; Lips, K.S.; Distler, C.; Kress, M. IL-1 beta potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2002 Oct;16(12):1497-1503.

Lips, K.S.; Kaltner, H.; Reuter, G.; Stierstorfer, B.; Sinowatz, F.; Gabius, H.J. Correspondence of gradual developmental increases of expression of galectin-reactive glycoconjugates with alterations of the total contents of the two differentially regulated galectins in chicken intestine and liver as indication for overlapping functions. Histology and histopathology. 1999 Jul;14(3):743-760.

Kaltner, H.; Lips, K.S.; Reuter, G.; Lippert, S.; Sinowatz, F.; Gabius, H.J. Quantitation and histochemical localization of galectin-1 and galectin-1-reactive glycoconjugates in fetal development of bovine organs. Histology and histopathology. 1997 Oct;12(4):945-960.

Kortje, K.H.; Aich, B.; Lips, K.; Rahmann, H. Cellular substructures in the optic tectum of Antarctic and temperate fish. J Zool. 1996 Feb;238:333-350.

Stichel, C.C.; Lips, K.; Wunderlich, G.; Muller, H.W. Reconstruction of transected postcommissural fornix in adult rat by Schwann cell suspension grafts. Experimental neurology. 1996 Jul;140(1):21-36.

Lips, K.; Stichel, C.C.; Muller, H.W. Restricted appearance of tenascin and chondroitin sulphate proteoglycans after transection and sprouting of adult rat postcommissural fornix. Journal of neurocytology. 1995 Jun;24(6):449-464.

Übersichtsarbeiten:

Beckmann, J.; Lips, K.S. The non-neuronal cholinergic system in health and disease. Pharmacology. 2013;92(5-6):286-302.

Kummer, W.; Lips, K.S.; Pfeil, U. The epithelial cholinergic system of the airways. Histochemistry and cell biology. 2008 Aug;130(2):219-234.